Leadership
The COPDforum leadership is comprised of renowned researchers/clinicians in COPD, who have contributed significantly
to the developments in this field. This global group represents some of the world's thought leaders in this area,
who are prominent in respiratory publications, international and local societies and research initiatives. Click on the
links below to learn more about the COPDforum leadership.
Leadership
Robert A. Stockley
MD, DSc, FRCP, Professor of Medicine
United Kingdom
Keeping up to date with the rapidly expanding knowledge and publications in COPD is becoming a
... Read AllKeeping up to date with the rapidly expanding knowledge and publications in COPD is becoming a daunting and almost impossible task
Place of work
Queen Elizabeth Hospital.
Experience
Robert Stockley is currently Professor of Medicine at the University Hospital Birmingham and Director of Research and Development for the University Hospital Birmingham NHS Foundation Trust.
Professor Stockley has a long-standing interest in chronic obstructive pulmonary disease (COPD) with particular reference to airway inflammation, proteinases and anti-proteinases, and especially the role of the neutrophils, bacteria and exacerbations. He acts as advisor to many pharmaceutical companies on the design and delivery of phase 2 and 3 clinical trials, and has been principal investigator for several large multinational trials in COPD. Professor Stockley organizes the UK alpha-1-antitrypsin deficiency database and established the international registry for the deficiency. He is currently coordinating multicentre trials of augmentation therapy and alveolar regeneration in patients with this deficiency. Since 1981, he has run a specialist clinic for patients with bronchiectasis, and has a special interest in bacterial colonization and bacterial load related to inflammation.
Professor Stockley has published more than 400 peer-reviewed papers, a selection of which is listed below
Recent publications
Sullivan AL, Dafforn T, Hiemstra PS, Stockley RA. Neutrophil elastase reduces secretion of secretory leukoproteinase inhibitor (SLPI) by lung epithelial cells: role of charge of the proteinase-inhibitor complex. Respir Res 2008;9(1):60.
Wood AM, Simmonds MJ, Bayley DL, Newby PR, Gough SC, Stockley RA. The TNF alpha gene relates to clinical phenotype in alpha-1-antitrypsin deficiency. Respir Res 2008;9:52.
Holme J, Tomlinson JW, Stockley RA, Stewart PM, Barlow N, Sullivan AL. Adrenal suppression in bronchiectasis and the impact of inhaled corticosteroids. Eur Respir J 2008 May 28. [Epub ahead of print]
Abusriwil H, Stockley RA. Bacterial load and exacerbations of COPD. Am J Respir Crit Care Med 2008;177(9):1048–9; author reply 1049.
Parr DG, Sevenoaks M, Deng C, Stoel BC, Stockley RA. Detection of emphysema progression in alpha 1-antitrypsin deficiency using CT densitometry; methodological advances. Respir Res 2008;9:21.
Cazzola M, MacNee W, Martinez FJ, Rabe KF, Franciosi LG, Barnes PJ, Brusasco V, Burge PS, Calverley PM, Celli BR, Jones PW, Mahler DA, Make B, Miravitlles M, Page CP, Palange P, Parr D, Pistolesi M, Rennard SI, Rutten-van Mölken MP, Stockley R, Sullivan SD, Wedzicha JA, Wouters EF; American Thoracic Society; European Respiratory Society Task Force on outcomes of COPD. Outcomes for COPD pharmacological trials: from lung function to biomarkers. Eur Respir J 2008;31(2):416–69.
Bayley DL, Abusriwil H, Ahmad A, Stockley RA. Validation of assays for inflammatory mediators in exhaled breath condensate. Eur Respir J 2008;31(5):943–8.
Sapey E, Bayley D, Ahmad A, Newbold P, Snell N, Stockley RA. Inter-relationships between inflammatory markers in patients with stable COPD with bronchitis: intra-patient and inter-patient variability. Thorax 2008;63(6):493–9.
Vijayasaratha K, Stockley RA. Reported and unreported exacerbations of COPD: analysis by diary cards. Chest 2008;133(1):34–41.
Wedzicha JA, Calverley PM, Seemungal TA, Hagan G, Ansari Z, Stockley RA; INSPIRE Investigators. The prevention of chronic obstructive pulmonary disease exacerbations by salmeterol/fluticasone propionate or tiotropium bromide. Am J Respir Crit Care Med 2008;177(1):19–26.
Pye A, Hill SL, Bharadwa P, Stockley RA. Effect of storage and postage on recovery and quantitation of bacteria in sputum samples. J Clin Pathol 2008;61(3):352–4.
Abusriwil H, Stockley RA. The interaction of host and pathogen factors in chronic obstructive pulmonary disease exacerbations and their role in tissue damage. Proc Am Thorac Soc 2007;4(8):611–7.
McNab GL, Ahmad A, Mistry D, Stockley RA. Modification of gene expression and increase in alpha1-antitrypsin (alpha1-AT) secretion after homologous recombination in alpha1-AT-deficient monocytes. Hum Gene Ther 2007;18(11):1171–7.