Leadership
The COPDforum leadership is comprised of renowned researchers/clinicians in COPD, who have contributed significantly
to the developments in this field. This global group represents some of the world's thought leaders in this area,
who are prominent in respiratory publications, international and local societies and research initiatives. Click on the
links below to learn more about the COPDforum leadership.
Leadership
Leonardo M. Fabbri
Professor of Respiratory Medicine
Italy
Place of work
Department of Oncology, Haematology and Pneumology Section of Respiratory Diseases University of Modena and Reggio Emilia Modena.
Experience
Leonardo Fabbri is Professor of Respiratory Medicine and Director of the Section of Respiratory Diseases of the Department of Medicine of the University of Modena and Reggio Emilia. He received doctorate in Medicine and Surgery from the University of Padua on 1972. He has been a Visiting Research Fellow at the Department of Respiratory Diseases of Tulane University and at the Cardiovascular Research Institute at the University of California, San Francisco, USA. Dr. Fabbri currently leads a multicenter research group carrying out clinical trials concerned with the role of inflammation in chronic obstructive pulmonary disease and asthma.
Dr. Fabbri has served as Editor of the European Respiratory Review and of the European Respiratory Monograph and Associate Editor of the European Respiratory Journal, and he is currently Associate Editor of the American Journal of Respiratory and Critical Care Medicine. He was a member of the Executive Committee of the Global Initiative on Asthma (GINA) from 1990 to 2001; member of the Scientific Committee of the Global Initiative on Obstructive Lung Disease (GOLD) from 1997 to 2005; Chairman of the Scientific Committee of GOLD from 2001 to 2004 and chairman of the Executive Committee of GOLD from 2004 to September 2005. Dr. Fabbri is currently President of the European Respiratory Society.
Dr. Fabbri has published more than 250 papers in peer-reviewed journals.
Representative papers from 2007 and 2008 are listed below.
Recent publications
Kiri VA, Fabbri LM, Davis KJ, Soriano JB. Inhaled corticosteroids and risk of lung cancer among COPD patients who quit smoking. Respir Med. 2008 Sep 13. Epub.
Turato G, Barbato A, Baraldo S, Zanin ME, Bazzan E, Lokar-Oliani K, Calabrese F, Panizzolo C, Snijders D, Maestrelli P, Zuin R, Fabbri LM, Saetta M. Nonatopic children with multitrigger wheezing have airway pathology comparable to atopic asthma.
Am J Respir Crit Care Med. 2008 Sep 1;178(5):476-82.
Boschetto P, Zeni E, Mazzetti L, Miotto D, Cascio NL, Maestrelli P, Marian E, Querzoli P, Pedriali M, Murer B, De Rosa E, Fabbri LM, Mapp CE. Decreased heme-oxygenase (HO)-1 in the macrophages of non-small cell lung cancer. Lung Cancer. 2008 Feb;59(2):192-7.
Crisafulli E, Costi S, Luppi F, Cirelli G, Cilione C, Coletti O, Fabbri LM, Clini EM.
Role of comorbidities in a cohort of patients with COPD undergoing pulmonary rehabilitation. Thorax. 2008;63:487-492.
Fabbri LM, Luppi F, Beghé B, Rabe KF. Complex chronic comorbidities of COPD.
Eur Respir J. 2008;31:204-212.
Maestrelli P, Ferrazzoni S, Visentin A, Marian E, Dal Borgo D, Accordino R, Fabbri LM. Measurement of exhaled nitric oxide in healthy adults. Sarcoidosis Vasc Diffuse Lung Dis. 2007;24:65-69.
Crisafulli E, Costi S, Fabbri LM, Clini EM. Respiratory muscles training in COPD patients. Int J Chron Obstruct Pulmon Dis. 2007;2:19-25.
Renda T, Baraldo S, Pelaia G, Bazzan E, Turato G, Papi A, Maestrelli P, Maselli R, Vatrella A, Fabbri LM, Zuin R, Marsico SA, Saetta M. Increased activation of p38 MAPK in COPD. Eur Respir J. 2008;31:62-69.
Fabbri LM, Boschetto P, Mapp CE. COPD guidelines: the important thing is not to stop questioning. Am J Respir Crit Care Med. 2007;176:527-528.
Papi A, Paggiaro P, Nicolini G, Vignola AM, Fabbri LM; ICAT SE study group. Beclomethasone/formoterol vs fluticasone/salmeterol inhaled combination in moderate to severe asthma. Allergy. 2007 Oct;62(10):1182-8.
Zeni E, Mazzetti L, Miotto D, Lo Cascio N, Maestrelli P, Querzoli P, Pedriali M, De Rosa E, Fabbri LM, Mapp CE, Boschetto P. Macrophage expression of interleukin-10 is a prognostic factor in nonsmall cell lung cancer. Eur Respir J. 2007 Oct;30(4):627-32.
Miotto D, Boschetto P, Cavallesco G, Zeni E, Querzoli P, Pedriali M, Chiarelli S, Fabbri LM, Mapp CE. Increased neurokinin-2 receptor expression in alveolar macrophages of smokers with COPD. Histopathology. 2007 Jul;51(1):128-31.
Fabbri LM, Rabe KF. From COPD to chronic systemic inflammatory syndrome?
Lancet. 2007;370:797-799.
Baraldo S, Bazzan E, Zanin ME, Turato G, Garbisa S, Maestrelli P, Papi A, Miniati M, Fabbri LM, Zuin R, Saetta M. Matrix metalloproteinase-2 protein in lung periphery is related to COPD progression. Chest. 2007;132:1733-1740.
Rabe KF, Beghé B, Luppi F, Fabbri LM. Update in chronic obstructive pulmonary disease 2006. Am J Respir Crit Care Med. 2007;175:1222-1232.
Miotto D, Boschetto P, Cavallesco G, Zeni E, Querzoli P, Pedriali M, Chiarelli S, Fabbri LM, Mapp CE. Increased neurokinin-2 receptor expression in alveolar macrophages of smokers with COPD. Histopathology. 2007;51:128-131.
La Vecchia C, Fabbri LM. Prevention of death in COPD. N Engl J Med.
2007;356:2211-2212.
Papi A, Canonica GW, Maestrelli P, Paggiaro P, Olivieri D, Pozzi E, Crimi N, Vignola AM, Morelli P, Nicolini G, Fabbri LM; BEST Study Group. Rescue use of beclomethasone and albuterol in a single inhaler for mild asthma. N Engl J Med. 2007 May 17;356(20):2040-52.
Calverley PM, Sanchez-Toril F, McIvor A, Teichmann P, Bredenbroeker D, Fabbri LM.
Effect of 1-year treatment with roflumilast in severe chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 2007;176:154-161.
Crisafulli E, Costi S, De Blasio F, Biscione G, Americi F, Penza S, Eutropio E, Pasqua F, Fabbri LM, Clini EM. Effects of a walking aid in COPD patients receiving oxygen therapy. Chest. 2007;131:1068-1074.
Chanez P, Wenzel SE, Anderson GP, Anto JM, Bel EH, Boulet LP, Brightling CE, Busse WW, Castro M, Dahlen B, Dahlen SE, Fabbri LM, Holgate ST, Humbert M, Gaga M, Joos GF, Levy B, Rabe KF, Sterk PJ, Wilson SJ, Vachier I. Severe asthma in adults: what are the important questions? J Allergy Clin Immunol. 2007 Jun;119(6):1337-48.
Kodric M, Shah AN, Fabbri LM, Confalonieri M. An investigation of airway acidification in asthma using induced sputum: a study of feasibility and correlation.
Am J Respir Crit Care Med. 2007 May 1;175(9):905-10.
Papi A, Paggiaro PL, Nicolini G, Vignola AM, Fabbri LM; Inhaled Combination Asthma Treatment versus SYmbicort (ICAT SY) Study Group. Beclomethasone/formoterol versus budesonide/formoterol combination therapy in asthma.
Eur Respir J. 2007 Apr;29(4):682-9.